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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d99ac0f65c69b26606754bab60df78e619e8ca052e1ac497c56f2ee61f4b2b1' 
  AND token = 'jN9SHPbSa3mRXne+meMuBRewkm9FDBNWjq3h7CaTqpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}