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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57b4e9090a69b6a03c75a0ddc506bac660ef90bdd06fec57b612b35a716a4f1d' 
  AND token = 'szUXXvM+kYkzOCQ+vi7yI+Q//DmdneN04fx0EXQBwoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}