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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27874242dd706249b3935c437d71ca2c4e354937f1788913fb7e47e4e866c7ce' 
  AND token = 'J5sxtgbBcxKmiDqcTeu6oS15mkZ/ikfY/bQ98FCjM0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}