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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0f5a1d8e6be82706d0a997c69f39dfb97df880e7b13442ef7d0a40f5bc7be90' 
  AND token = 'Ium+csU4N3S3iguyOEmimj0yDzUhXuAcQaE+xCrL8F4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}