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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a121fc07790c894b4b0b2a0783b8f9324311a49bafc5405a7196cc836dcfc286' 
  AND token = 'vjxrXkI09Ccorg7oyyhA2MQL2vc9KcBxytMz0zETr+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}