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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b049e4c1ac63b14079005de3c1f6d60606b661f9b6b188346df7b45c3dd1a86' 
  AND token = 'VRLDFuuit61AHxmehi9A1EtlxqmujamL//GZPlZaZuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}