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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a6b910c703940502451d7db320c3cebbb33f403f8fe415f9b3a4c7a056579f0' 
  AND token = 'oP3kBrj7sEfzoBlEnS6qPUMl1TJdOg12zZJCKdPpRfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}