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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5321e2348f99a0ff1fe73ee2a3dccea4c743ac54ae543a81e8b3ec6da35212cc' 
  AND token = 'QJSkOsgBPko3K+ZsEu2fxMW04oo73Y3c/mqVT7qyx6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}