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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a18dfd929cd052d59789889b03c4b6cb5eba7cc248ffaa64355b85c054c046d7' 
  AND token = 'ZB85KXJD9MiTnj6piz/S89BIOHbmS9zKXDD+3rtaf+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}