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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2532473fc97cd34a7b31c831f4f3cce5d85a099ea6ba3feea2f182e441ec8b8c' 
  AND token = '0Y+sfhz6FSOnCnlwnfSSSNTJb024Y6XCyMzI/b9lH4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}