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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d5206fcd4f7fcadf44ded6f03ec9b98779917ca278dc0b02ff5add8bd92d8d' 
  AND token = '6JUUZJrcE1RdFSHeoN7RmxhbrXSK0zfPdciLUvFYu7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}