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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b683aff22214ff975d5d406228653b25a1e199dcd6b3f48441acdcbebf4d6e05' 
  AND token = 'Z3V9ofed6NT0mnmfuvkezaC8xMaFWRBOqpPleSmHryI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}