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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e3e95d178fc8c92e63193093a3a8accadb865e450c935de587700c0ef74826' 
  AND token = 'nFvy42YW760tHPuHuoneFBlxabGpSkWz0gDtecYRu18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}