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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43a3dda3c80e89443337dcda0179812f7c6ea4ae86a2926235ddee7ba94d078' 
  AND token = 'jEJmUPQcRiFBNkeymVqBBoPM3Lhjit4SwcYnjehjXxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}