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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aca379816f252aff2e2167ea9786f34b6a77348ec3bf8381495188da65c12291' 
  AND token = 'sH95Xzk7JhlOmJbDiDNccSldbZrX3hV7Y4AUX2Gz1Q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}