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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ff9209ecbc5f7285e4475d95d3423b3b0f8bd2d8c3795ce7a67c33e6819e7f5' 
  AND token = 'Q+gkZhaTfWLdBkn1UDNugy7eKxhd2gPtSVRqU0yZrxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}