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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e66081a31abf28fb3d36d00c1e55c6fee302d3af443987843ea30d084280512' 
  AND token = 'cEF8Bqe2W5P0kXtoBOMvn0qvFF3rj/gCJD/FtJaviR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}