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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78943ff13c2098f20cb943d4b44b3ba844c342472f971f397a952aacf1b71c5d' 
  AND token = 'zWGGIe8v++cS1ZSOsZWePA5Hsh7vMTm+LzI7HDTJkFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}