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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa896c5607b3d000a5e5fe5c0f8dd2b07a815f207b36e50660694240f369a429' 
  AND token = 'U7y//ed3fEK/AMoHhz1Qu7HIZaHuAw3Dv7YnJPZAhho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}