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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e1bd4c8625609d5c84dbd9c608f32ae7723da9425da94cbc40d3e260fe86e0f' 
  AND token = 'calg6J3lgH8B1PNewmus7EKde2euUSxIjBUywgvG8HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}