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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65fdf17a17dc3c4b7e3814114b948e0070d8f551464b9db771f0ac11a685672b' 
  AND token = 'Cpy09D9pCOZbpE4/zfb2SUMYrEHbyN+AibAIQx8CFS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}