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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b00cab4de784bd1f2ab4b2b5511fa7106e478e3a36d246a37ffd21c482402037' 
  AND token = '4+6Hv2JbA1v1mFcgoAvo8UkjyrXsGk8c341PIwqmSqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}