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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1af7eea91f5d22c73c42d429512cca5ef1b430fda20311dde45df2cbaf5b7406' 
  AND token = '3eURI6XsFw8H7mOSiLZ4ThPCTIyvM7yaZ8q43uizi0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}