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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e6a577db7d34eb0a306fa39106165e994f19dbab864ed13ec936e1e145cf849' 
  AND token = 'ThV2G1bc2f+Cx+LK2yHTYywlXImvwijUuHcLC3sJE98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}