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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b1eace4317e6f4ddd2e536e5da73c602b922c26e4908cfbcfed9d0b9aae4db9' 
  AND token = 'X0nf06XMMWjeoOgcHp7AVIS8+1vq3CGBV+33TLtdVGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}