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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72c3db87dbbd4321438868cfbe45ea0f1e3d59aa2dd3b01862499730a1a99e53' 
  AND token = 'muiegg0HO/TnwLAYavnRaqbvSR6+wS4lk1y/j5b9uwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}