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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36d7a907a70c92e390792d44be72807209ff98c58c7ccaf28dd74f435285b270' 
  AND token = 'qIQFcnobe5LOSEJcIWiBR4PpO2hodF6N3tQFpDBQeW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}