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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac95d1c112b851ad38efef7c6ccfe224ee1433edfcd551b89bf9053525ba37c' 
  AND token = 'e9Qt5lUrU4Zor+218zsVKTS9dGMnJ22dlPPY8WVTQ8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}