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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '622552200fd8823d06ab3cf9c314b4a296a7180989a02f784536a5d4045411a9' 
  AND token = 'wa2V67ZKsSs3ea4JxorIjDOvpwuNyjpHcXAE8Q4pkqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}