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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a356e5611d10185b4e4430f79a8314fc8b5e9eb94e2b79e11e109c52eda3784' 
  AND token = 'zTlUL40LbTJHsWZEViXH4GnsaeMwRXmMafgEodhEzKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}