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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a74597583e33d1634f2220fe48fe410b4bd725c666f097b349536a9b966a91d' 
  AND token = 'HEnz18dMbmTW8tF8i4xj36id3XPx2BKJ5odERmxZDR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}