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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da09981f993a03d80bfbcb1bff229c5a38230e64daf39112b9c1002afc8833ad' 
  AND token = 'uGT2GtP2c6IDqDTyliavm2LvWDoowz/g7PgS3knHsfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}