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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eedb99e65056a532cc0b6eb293649cc24e5241bb7be4c79e6f74d9dcca3d518' 
  AND token = 'V1sAgqIw582Nh2uY2ghRUtAyE8npL3pMplZ4q8GJUR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}