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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0c49aa9dc6e87a78989a329e92cbd581efbf4a9bb890436ec20fc49d21cef0d' 
  AND token = 'mWPNM+newQlxjPR34nFTiNKpvT9EDr+odh3cO5mdi/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}