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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a173367fbebc4f83220f4ab6e37ecc5e271dcc0da2421f80d0ee0069222e3e' 
  AND token = '1MNxAD9tJ+GYgWY5qMJNJ40iWTFk/ZY1G/Fwak6UAsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}