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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f351177a85c2067272ca89e4023a29eed6cf5c21311eb9ef46ec4d273e9884a' 
  AND token = 'Y1BNpO8qjLA53p+NMcwQW70kZp+Kd4mXcJJ/1NL0d84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}