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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8e1ed0c7afd62d4cd212d03fe7853cd66a706b2b7e10fc59f97d568e7ca8339' 
  AND token = '+WFr0jtdxTci/CYOqyBZpSFuTdEOCLIqTuLjKklXaA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}