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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff601e51d5fc4de23420140b109b49841c25c734cd18a0167753f43bc9c7721c' 
  AND token = 'vJ9Ypbgan4CuTuRHYSiSbYdnuoJ45BXlrZ5smOmZLGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}