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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '318603d72999a99d00601e54e2a1aee24213a7aca98221c13b3ad0aa02fa2f32' 
  AND token = '3nYtTlPjmjIWkilfNNgaAhVVgq49G2M+V4EmzNEgFKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}