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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4dbd41492b1dafbec822e183c8dba2ebfd81ec2b2f55fedf333043011c9f148' 
  AND token = '2NzHiV8AbOaupcnruXf6UP28vjPHBRCY+AmoAdPcQ3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}