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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b75eda897f6a14341f22407cd3d8cc486e01ab9c5a46e551f3d06cd9bec5bd8' 
  AND token = 'UhmarD9jSPEFl2TQ1lh2ZzgVDPG2B2QiQndhMTjUQWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}