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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42216ba4acf6fd0b9d25e8ddfaee3750435b3cd364a47f4840d1196f742ee597' 
  AND token = 'x3eZ8Rn+UdaiHh7gWZNQNaachd/ER3AiY/RiJdtZY68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}