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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4cbd00ce575c802b4d93e9242744edb89cc8cd3d605a226bee89e1520bb1479' 
  AND token = '05w4fOdA91Pkcarck0ThXb+gxqNz2Mcf60UJZGCzkQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}