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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b356b217b8b2a3ba10f8f078807f094e0a0bf3875c0e5a2c5236b1e707be725' 
  AND token = 'IiL4mW2K+ldouk2HeBbaEDiROY1Gu19xiXsgwtBzkrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}