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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44450a76001728b8b1028cfe25ae734eff3f936e6c734d3d2892791d82a2a1ee' 
  AND token = 'n5Ka9tWMhMyjEo86qoY9DyAXqpeXjAcXJsqKyFB3dkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}