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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f6511a83474de8917eb763a0dd6da93b58a69c95e66b9faefffacb7e71c58b7' 
  AND token = 'kZ35074RjegTSQC/TTsStTOczFNZxumAiPl9xDO1IJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}