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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce2369872ecc137a51fa6645e4b8bcf3605b7cbc60052e77fef2b96e8039443c' 
  AND token = 'CrLeRRDtEbuuiXAV+vAJP39q8hzEBEAYHePxYlWT4IE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}