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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af5fac251500f7b928dcff15786c656f0b9f29c77576374d1da1f7970e71e909' 
  AND token = 'tNL3Z7Hw7QwAjjFRS+gCEq60qK/qXo6cgynP/tYPWLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}