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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f832a5429a6b4d86768a34fef7e7b1babc70e06e01aa2b2c0176ee73f7f75843' 
  AND token = 'tja1+h8FIDbrPmPieSIKikUvDvqqbXDObYl0xM2qHyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}