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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ef1937fb2d0211d0c471cc621f3c0c049ab16cf5e85234a1b4e0e6e33cbd844' 
  AND token = 'UhdzGbJbOr6ANFvr3Kkq9d2NfAmq5d01eezpLT4YKZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}